Silica
Silica is the "getter" material from what I understand.
You can't really create 100% diffusion proof polymers - or more so insulation materials.
That means even if the panel isn't breached, over the years and decades a fridge exists, some gases get into that panel, no matter what.
And the insulation quality QUICKLY declines with even minimal gas intrusion.
A "getter" collects those molecules that do get in there by chemical means and/or physical means (adhesion).
It's in there, but the panel isn't "filled" with it.
As far as I know, basically, ALL VIPs contain such a getter, and usually, we're talking a few grams from what I've seen, not a full panel.
You certainly know the silica packets that come in shoes or such.
Same principle, similar material, just different application.
On the topic of integrity.
Once the VIP is breached, it's trash.
You can't cut it out and replace it, like you can't replace the foamed insulation on any fridge.
If it's the door, you can of course replace the entire door, but that's it.
However, once they are assembled, the likelihood of a breach is VERY small.
You have basically a sandwich of the metal cabinet, a bit of foamed insulation, the VIP, then some more foamed insulation and then the plastic liner.
There isn't much mechanical stress on that system.
To get the VIP damaged, you'd have to damage and/or breach either the inner or outer liner and the foam holding the panel in place.
Of course, if you transport the fridge and drop it from a significant height on a corner, sure, that certainly can happen.
But at that point, you would have the same issue either way: Broken in shipping, no longer sellable.