The original Sanders Court and Cafe in Corbin, Ky., has been restored and is worth a visit if you're in the area. It's only a few miles from I-75. There hasn't been any attempt to recreate the original menu; it's standard KFC stuff, but you eat in a 1940s dining room with hickory furniture!
Many of the biographies of Col. Sanders say that he had to close the cafe in 1955 because I-75 drew the traffic away, but I-75 was nowhere near being built in 1955 and the cafe is right on current US 25 so I'm not sure what happened.
