Hmmm.. Maybe a version of Gain that I can use and doesn't make me itch... There's something in all versions of Gain, Gain Fabric softener, all of the Unstoppables, liquid Downy, and Tide with Febreze that doesn't agree with my skin. Whatever gives the clothes that "lasting" kind of sweet scent. As long as it's not used on undies, socks, towels, or pajamas (close contact with skin) I'm fine, but if something gets washed in something it shouldn't be I'm dancing up and down like ants in my pants. We usually use Tide, either Original or Clean Breeze (HE), and I did try the Tide PurClean shortly after it appeared on shelves. I thought it did a fine job of cleaning, and had a pleasant scent, but the scent was a little on the weak side for me. I like enough scent to know the clothes are clean but not smell like the perfume section of your favorite department store. Usually just Tide and Meijer's store brand of free and clear liquid softener. Maybe the new Gain, being a more natural detergent will leave that ingredient out. Will definitely give it a try when it goes on sale.