@whirlcool
My late, beloved Ridgeback (named Korky; passed away Feb 2010 at fourteen years of age) once vomited on the bed's fitted bottom sheet. Soaked through the sheet, the mattress topper, and moistened the mattress pad (did not soak through to mattress. In addition, comforter and cover were soiled, by direct contact with ground zero.
In two loads, I had everything washed and dried and back on the bed. I did have to take the fitten bottom sheet outside and shake off the debris before washing. Of course, this was live as it happened, not a forgotten item in a closet, but I didn't have to go to a laudromat and I did it all at home (in the middle of the night, as this happened about midnight).
The one caveat is that it was summer and I was using a lightweight IKEA synthetic comforter that was only full/queen size. Not warm enough for winter but just right for summer. Had I been using one of the thicker winter-weight king size comforters, I'd have had to go to the laundromat, it won't fit in my 3.5 cu ft Frigidaire (I have a lightweight king size that WILL fit, but not the heavier winter-weight model).
Someday my spider will break and I'll need to go shopping. Most likely one of the 4.0+ cu ft models will accomodate everything that I wash, including king size comforters. However, I'm not the type to throw something out that works. So the current washer---which was mid-size when it was purchased, with 3.7 cu ft WP's being the largest on the market in early 2006---will be the daily driver until such time as the spider fails.