Sort clothes based on fabric, ( cotton, permanent press, delicate, etc.). Sort again by color (whites, lights, brights, darks). Pre-treat any stains with Resolve Spray and wash, the aerosol, not the pump type. (Even the aerosol isnt as good as it was before Resolve took over, and the pump type is awful).
For really bad stains, get a stain guide. (cool water soak for blood, alcohol and hairspray for ink, etc etc. ) But for most basic things, the aerosol Spray and Wash does the trick.
Hot water, Oxydol Powder detergent, and Clorox for whites, with a touch of Mrs. Stewarts Bluing in the final rinse, along with some generic watery gallon jug supermarket softener. Whites get an extra rinse cycle, because of the Clorox bleach.
Hot water, Era liquid detergent, and oxygen bleach for lights, with the same generic softener.
Warm water and Era liquid detergents for brights, with the same generic softener.
Cold water and Era liquid detergent for darks, with the same generic softener.
Rugs and such get a hot water wash with Oxydol powder detergent, no softener.
Delicates get a cold water wash with Woolite, and the same generic softener.
Permanent press fabrics get washed on the perm press cycle, (though mine isnt a true perm press, its a combination of settings that is equivalent) with Era liquid detergent and the generic softener.
Everything except rugs and delicates gets a run through the dryer on the auto setting, with a Bounce dryer sheet. Delicates air dry on a rack, rugs air dry on the line outside.
Dont forget to use the permanent press cycle on your washer and dryer for those type fabrics, if you have one, and keep them seperated form cotton fabrics for washing.
If you cannot find the old fashioned watery gallon jug type softener, dilute you softener with 1 part water to 1 part softener for regular, 2 part water to 1 part softener for ultra. The liquid softener for me is more to help with rinsing, and I dont want that thick goop they sell now. The Bounce dryer sheet combined with the watered down softener makes everything soft, static free, and smells just like my childhood. (I know many on here hate softener, and I tried to live without it, really I did, but I like EXREMELY soft clothes and towels, and short of washing everything in rainwater or getting a whole house water softener, fabric softener is the only way to acheive that here. Your mileage may vary.)
Also don't forget to check items that were heavily stained before putting them in the dryer, if the stain is still there, it will need further treatment and re-washing, as drying it would cook in the stain.
Last note, these are the detergents that seem to give the desired results here. Depending on your water conditions, machine type, and general types of soil on your laundry, other detergents may work better in your area, ask around and experiment.