As for movies...
I would agree that there have been some fabulous cars in the James Bond movies... but the best has to go to Goldfinger... which I believe is where they debuted his Aston Martin... and includes the Continental and Ranchero described earlier in this thread, but also a great chase scene with the Aston Martin, a (then new) Mustang, and several Mercedes pontons (I recall they were 220S). Bond films often had great cars, but somehow had taken on an AMC sponsorship in the mid 70s, and I think it was The Man With the Golden Gun that includes a chase scene starting at an AMC dealer (in Thailand?) and ends with the villain converting his AMC Matador coupe to fly...
For a couple totally different chase scenes/cars, of course there is Bullitt, with the Charger/Mustang chase 'won' by Steve McQueen in the Mustang... or It's a Mad, Mad, Mad World, a great movie filled with 1962 (and other year) Chrysler products including the Imperial convertible, a Belvedere wagon, a Polara convertible, several stripper Plymouth and Dodge police cars, and more...
And being a Mopar guy, who couldn't appreciate the little car that could, Dennis Weaver in his Plymouth Valiant, outmaneuvering the trucker in Steven Speilberg's first movie, Duel.