I'm not sure what you're asking, here. Do you mean "do you shake the bottle of dishwashing detergent before you squirt it into the sink?"
If so, the answer is no. I just pick the the bottle from under the sink and squirt a little into the sink.
If I've misunderstood your question, please clarify and I'll try again. Sorry, it's early and I haven't had my first cup of coffee, yet, LOL.